Cognitive rehabilitation in patients with Parkinson’s disease

Czech version

Authors: V. Plzáková ^1,2; T. Nikolai ¹
Authors‘ workplace: Laboratoř neuropsychologie, Neurologická klinika 1. LF UK a VFN v Praze ¹; Rehabilitační ústav Kladruby ²
Published in: Cesk Slov Neurol N 2020; 83(1): 14-20
Category: Review Article
doi: https://doi.org/10.14735/amcsnn202014

Overview

Cognitive impairment is recognized as an important non-motor symptom of Parkinson´s disease (PD) and it can be particularly characterized by disruption of executive functions, memory, visuospatial functions and attention. Cognitive decline may already occur in early stages of the PD and it can progress from mild cognitive impairment in PD up to dementia in PD. Cognitive rehabilitation (CR) represents one of non-pharmacological approaches to remediation of cognitive impairment in PD patients. At present, we have individual and group non-computerized and computerized approaches to CR. Currently, CR is not an evidence-based approach in PD patients, because of a limited number of studies. The report compares the research of efficiency of non-computerized CR in comparison with efficiency of computerized CR and combined approach. For this purpose, we searched for the research published between 2004 -2018. The aims of the report are to analyze current research of CR in PD patients and to compare the efficiency and benefits of computerized, non-computerized CR and combined approach for PD patients. The purpose of the report is to point out the new approaches and innovations in the field of CR in patients with neurodegenerative disorders.

The Editorial Board declares that the manuscript met the ICMJE “uniform requirements” for biomedical papers.

Keywords:

Parkinson´s disease – cognitive rehabilitation – computerized cognitive rehabilitation – non-computerized cognitive rehabilitation – combined rehabilitation – cognitive dysfunction

Sources

1. Chen L, Yu C, Zhang N et al. Cognitive impairment in patients with Parkinson’s disease: a 30-month follow-up study. Clin Neurol Neurosurg 2016; 151: 65–69. doi: 10.1016/ j.clineuro.2016.09.021.

2. Hurtado Gonzalez CA, Ladera V, Perea MV et al. Mild cognitive impairment in idiopathic Parkinson‘s disease without dementia. Biomed Res 2017; 28(8): 3635–3640.

3. Das D, Biswas A, Roy A et al. Cognitive impairment in idiopathic Parkinson‘s disease. Neurol India 2016; 64(3): 419–427. doi: 10.4103/ 0028-3886.181533.

4. Dubois B, Pillon B. Cognitive deficits in Parkinson’s disease. J Neurol 1996; 244(1): 2–8. doi: 10.1007/ PL00007725.

5. Litvan I, Goldman JG, Tröster AI et al. Diagnostic criteria for mild cognitive impairment in Parkinson‘s disease: Movement Disorder Society Task Force guidelines. Mov Disor 2012; 27(3): 349–356. doi: 10.1002/ mds.24893.

6. Svenningsson P, Westman E, Ballard C et al. Cognitive impairment in patients with Parkinson’s disease: diagnosis, biomarkers, and treatment. Lancet Neurol 2012; 11(8): 697–707. doi: 10.1016/ S1474-4422(12)70152-7.

7. Nikolai T, Bezdíček O, Vyhnálek M et al. Mírná kognitivní porucha: diagnostická jednotka nebo stadium předcházející demenci. Cesk Psychol 2012; 56(4): 374–390.

8. Kim KS, Kim BJ, Kim KH et al. Subjective and objective caregiver burden in Parkinson’s disease. Taehan Kanho Hakhoe Chi 2007; 37(2): 242–248. doi: 10.4040/ jkan.2007.37.2.242.

9. Pedersen KF, Larsen JP, Tysnes OB et al. Prognosis of mild cognitive impairment in early Parkinson disease. JAMA Neurol 2013; 70(5): 580–586. doi: 10.1001/ jamaneurol.2013.2110.

10. Aarsland D. Cognitive impairment in Parkinson‘s disease and dementia with Lewy bodies. Parkinsonism Relat Disord 2016; 22 (Suppl 1): S144–S148. doi: 10.1016/ j.parkreldis.2015.09.034.

11. Yang Y, Tang BS, Guo JF. Parkinson’s disease and cognitive impairment. Parkinsons Dis 2016; 2016: 6734678. doi: 10.1155/ 2016/ 6734678.

12. Hindle JV, Watermeyer TJ, Roberts J et al. Cognitive rehabiliation for Parkinson‘s disease dementia: a study protocol for a pilot randomised controlled trial. Trials 2016; 17(1): 152. doi: 10.1186/ s13063-016-1253-0.

13. Leung IH, Walton CC, Hallock H et al. Cognitive training in Parkinson disease: a systematic review and meta-analysis. Neurology 2015; 85(21): 1843–1851. doi: 10.1212/ WNL.0000000000002145.

14. Clare L, Woods R. Cognitive training and cognitive rehabilitation for people with early-stage Alzheimer‘s disease: a review. Neuropsychol Rehab 2004; 14(4): 385–401. doi: 10.1080/ 09602010443000074.

15. Gates NJ, Sachdev PS, Fiatarone Singh MA et al. Cognitive and memory training in adults at risk of dementia: a systematic review. BMC Geriatr 2011; 11: 55. doi: 10.1186/ 1471-2318-11-55.

16. Kennedy MR, Coelho C, Turkstra L et al. Intervention for executive functions after traumatic brain injury: a systematic review, meta-analysis and clinical recommendations. Neuropsychol Rehabil 2008; 18(3): 257–299. doi: 10.1080/ 09602010701748644.

17. Clare L, Linden DE, Woods RT et al. Goal-oriented cognitive rehabilitation for people with early-stage Alzheimer disease: a single blind randomized controlled trial of clinical efficacy. Am J Geriatr Psychiatry 2010; 18(10): 928–939. doi: 10.1097/ JGP.0b013e3181d5792a.

18. Watermeyer TJ, Hindle JV, Roberts J et al. Goal setting for cognitive rehabilitation in mild to moderate Parkinson’s disease dementia and dementia with Lewy bodies. Parkinsons Disease 2016; 2016: 8285041. doi: 10.1155/ 2016/ 8285041.

19. Simon SS, Yokomizo JE, Bottino CM. Cognitive intervention in amnestic mild cognitive impairment: a systematic review. Neuroscience 2012; 36(4): 1163–1178. doi: 10.1016/ j.neubiorev.2012.01.007.

20. Levine B, Robertson IH, Clare L et al. Rehabilitation of executive functioning: an experimental – clinical validation of goal management training. J Int Neuropsychol Soc 2000; 6(3): 299–312. doi: 10.1017/ S1355617700633052.

21. Cicerone KD, Dahlberg C, Kalmar K et al. Evidence-based cognitive rehabilitation: recommendations for clinical practice. Arch Phys Med Rehabil 2000; 81(12): 1596–1615. doi: 10.1053/ apmr.2000.19240.

22. Pena J, Ibarretxe-Bilbao N, Gacía-Gorostiaga I et al. Improving functional disability and cognition in Parkinson disease: randomized controlled trial. Neurology 2014; 83(23): 2167–2174. doi: 10.1212/ WNL.0000000000001043.

23. Sinforiani E, Banchieri L, Zucchella C et al. Cognitive rehabilitation in Parkinson‘s disease. Arch Gerontol Geriatr Suppl 2004; 9: 387–391. doi: 10.1016/ j.archger.2004.04.049.

24. Hindle JV, Watermayer TJ, Roberts J et al. Goal-orientated cognitive rehabilitation for dementias associated with Parkinson‘s disease pilot randomised controlled trial. Int J Geriatr Psychiatry 2018; 33(5): 718–728. doi: 10.1002/ gps.4845.

25. París AP, Saleta HG, de la Cruz Crespo Maraver M et al.Blind randomized controlled study of the efficacy of cognitive training in Parkinson‘s disease. Mov Disord 2011; 26(7): 1251–1258. doi: 10.1002/ mds.23688.

26. Mohlman J, Chazin D, Georgescu B. Feasibility and acceptance of a nonpharmacological cognitive remediation intervention for patients with Parkinson disease. J Geriatr Psychiatry Neurol 2011; 24(2): 91–97. doi: 10.1177/ 0891988711402350.

27. Sammer G, Reuter I, Hullmann K et al. Training of executive functions in Parkinson‘s disease. J Neurol Sci 2006; 248(1–2): 115–119. doi: 10.1016/ j.jns.2006.05.028.

28. Nombela C, Bustillo PJ, Castell PF et al. Cognitive rehabilitation in Parkinson’s disease: evidence from neuroimaging. Front Neurol 2011; 2: 82. doi: 10.3389/ fneur.2011.00082.

29. Adamski N, Adler M, Opwis K et al. A pilot study on the benefit of cognitive rehabilitation in Parkinson’s disease. Ther Adv Neurol Disord 2016; 9(3): 153–164. doi: 10.1177/ 1756285616628765.

30. Zimmermann R, Gschwandtner U, Benz N et al. Cognitive training in Parkinson disease: cognition-specific vs nonspecific computer training. Neurology 2014; 82(14): 1219–1226. doi: 10.1212/ WNL.0000000000000287.

31. Cerasa A, Gioia MC, Salsone M et al. Neurofunctional correlates of attention rehabilitation in Parkinson’s disease: an explorative study. Neurol Sci 2014; 35(8): 1173–1180. doi: 10.1007/ s10072-014-1666-z.

32. Edwards JD, Hauser RA, O’Connor ML et al. Randomized trial of cognitive speed of processing training in Parkinson disease. Neurology 2013; 81(15): 1284–1290. doi: 10.1212/ WNL.0b013e3182a823ba.

33. Reuter I, Mehnert S, Sammer G et al. Efficacy of a multimodal cognitive rehabilitation including psychomotor and endurance training in Parkinson‘s disease. J Aging Res 2012; 2012: 235765. doi: 10.1155/ 2012/ 235765.