Recommendations for the use of arterial spin labeling in clinical neuroimaging
Authors:
Y. Prysiazhniuk 1,2; D. Kala 1; ; Z. Holubová 2; B. Jurášek 2; L. Michal 1; J. Šanda 2; P. Janský 3; J. Tintěra 4; J. Petr 5,6; M. Kynčl 2; J. Otáhal 1
Authors‘ workplace:
Ústav patologické fyziologie, 2. LF UK, Praha
1; Klinika zobrazovacích metod, 2. LF UK a FN Motol, Praha
2; Neurologická klinika, 2. LF UK a FN Motol, Praha
3; Pracoviště radiodiagnostiky a intervenční radiologie, IKEM, Praha
4; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical, Cancer Research, Drážďany, Německo
5; Department of Radiology and Nuclear, Medicine, Amsterdam Neuroscience, Amsterdam University Medical, Center, Location VUmc, Amsterdam, Nizozemsko
6
Published in:
Cesk Slov Neurol N 2025; 88(1): 22-31
Category:
Review Article
doi:
https://doi.org/10.48095/cccsnn202522
Overview
Arterial spin labeling (ASL) is a non-invasive MRI method used to image cerebral perfusion. Given increasing concerns regarding the use of gadolinium-based contrast agents and significant technical advancements in ASL implementation, the method is gaining attention in various diagnostic applications. This review article aims to familiarize readers with the fundamentals of ASL sequence implementation in neuroradiology, discuss optimal scanning parameters for achieving the highest quality and accuracy in data interpretation, and provide an overview of its diagnostic applications in the areas of cerebrovascular diseases, neuro-oncology, epilepsy, and neurodegeneration. Furthermore, we present illustrative radiological cases and explore the potential future developments of non-invasive ASL techniques.
Keywords:
Neuroimaging – magnetic resonance imaging – perfusion imaging
Sources
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Paediatric neurology Neurosurgery NeurologyArticle was published in
Czech and Slovak Neurology and Neurosurgery
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