A Registry of Mechanical Recanalization Procedures in Acute Stroke – Pilot Results from a Multicentre Registry

Czech version

Authors: M. Roubec ¹; M. Kuliha ¹; D. Školoudík ¹; D. Šaňák ²; K. Langová ³ ; D. Krajíčková ⁴; E. Vítková ⁴; M. Kusyn ⁵; Z. Eichlová ⁶; R. Havlíček ⁷; P. Kešnerová ⁸; Širší Kolektiv Spolupracujících:; V. Procházka ⁹ ; T. Jonszta ⁹; J. Krajča ⁹; D. Czerný ⁹; R. Herzig ⁴; D. Václavík ⁵; J. Krátký ¹⁰; D. Kučera ¹¹; A. Tomek ⁸
Authors‘ workplace: Komplexní cerebrovaskulární centrum, Neurologická klinika LF OU a FN Ostrava ¹; Komplexní cerebrovaskulární centrum, Neurologická klinika LF UP a FN Olomouc ²; Ústav lékařské biofyziky, LF UP v Olomouci ³; Komplexní cerebrovaskulární centrum, Neurologická klinika, LF UK a FN Hradec Králové ⁴; Iktové centrum, Neurologické oddělení, Vítkovická nemocnice Ostrava a. s. ⁵; Komplexní cerebrovaskulární centrum, Neurologické oddělení, Krajská nemocnice Liberec, a. s. ⁶; Komplexní cerebrovaskulární centrum, Neurologické oddělení, ÚVN Praha ⁷; Komplexní cerebrovaskulární centrum, Neurologická klinika 2. LF UK a FN v Motole, Praha ⁸; Komplexní cerebrovaskulární centrum, Radiodiagnostický ústav LF OU a FN Ostrava ⁹; Iktové centrum, Radiologické oddělení, Vítkovická nemocnice Ostrava a. s. ¹⁰; Iktové centrum, Interní oddělení, Vaskulární centrum, Vítkovická nemocnice Ostrava a. s. ¹¹
Published in: Cesk Slov Neurol N 2015; 78/111(2): 205-208
Category: Short Communication
doi: https://doi.org/10.14735/amcsnn2015205

Overview

Background:
Acute cerebral artery occlusion is the most common cause of ischemic stroke. Early recanalization is associated with a significantly higher chance of achieving patient self‑ sufficiency and reducing mortality. Over the recent years, pharmacological recanalization methods were joined by mechanical methods. The aim of the registry is to map geographic availability and to assess safety and efficacy of mechanical recanalization techniques in routine clinical practice.

Methods:
All consecutive acute ischemic stroke patients treated with mechanical recanalization techniques in selected comprehensive cerebrovascular and stroke centers in the Czech Republic have been prospectively registered. Demographic data, stroke severity, grade of recanalization, patient clinical outcome and frequency of symptomatic intracranial hemorrhage (SICH) were analyzed in the pilot study and are presented.

Results:
A total of 353 patients (210 men, mean age 66.0 ± 13.1 years) with acute ischemic stroke and acute occlusion of the carotid or intracranial artery, treated using mechanical technique were consecutively registered to a multicentre registry between January 1, 2006 and September 21, 2014. The median of baseline NIHSS score was 16 points. Recanalization (TICI 2b‑ 3) was achieved in 58.6% and self‑ sufficiency after three months (modified Rankin Scale, mRS 0– 2) in 45.3% patients. SICH occurred in 4.2% patients and 3- month mortality was 26.1%.

Conclusion:
The organization of care for ischemic stroke patients in the Czech Republic is at a good level with availability of intravenous thrombolysis as well as mechanical recanalization methods. Endovascular procedures appear to be safe and highly effective with respect to arterial recanalization.

Key words:
stroke – registry – arterial occlusion – mechanical recanalization – therapy

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manuscript met the ICMJE “uniform requirements” for biomedical papers.

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