A Coagulopathy Following Craniocerebral Injury in Children and Adolescents

Czech version

Authors: M. Benčo ¹; J. De Riggo ¹; S. Nosáľ ²; M. Fedor ²; J. Šutovský ¹; R. Opšenák ¹
Authors‘ workplace: UN Martin Neurochirurgické oddelenie ¹; UN Martin Klinika detskej anestéziológie a intenzívnej medicíny JLF UK v Martine ²
Published in: Cesk Slov Neurol N 2012; 75/108(4): 432-437
Category: Original Paper

Overview

Aim:
To examine a relationship between coagulation parameters (prothrombin time, international normalized ratio, activated partial thromboplastin time, thrombin time and platelet count) and outcome in children after isolated craniocerebral injury.

Methods:
A retrospective study included 51 children (33 males and 18 females) aged 1–17 years, who undergone a surgery between 1. 1. 2005 and 1. 3. 2011. Coagulation parameters, examined within 6 hours after the injury, were compared for different types of craniocerebral injury and correlated with neurological status after injury and after treatment.

Results:
Coagulation parameters correlated with neurological status after injury and after treatment and differed significantly for different types of craniocerebral injury (except platelet count).

Conclusion:
A coagulation disorder occurring after an isolated craniocerebral injury in children is a negative prognostic factor that requires an urgent and aggressive therapy.

Key words:
craniocerebral injury – coagulopathy – prognosis

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