New pharmacological options in the treatment of Alzheimer‘s disease

Česká verze

Authors: L. Kleinová ^1,2; J. Cerman ²; J. Hlávka ³; J. Hort ²
Authors place of work: Všeobecné lékařství, 1. LF UK, Praha ¹; Kognitivní centrum, Neurologická klinika 2. LF UK a FN Motol, Praha ²; Schaeffer Center for Health Policy and Economics, University of Southern California, Los Angeles, USA ³
Published in the journal: Cesk Slov Neurol N 2022; 85(6): 462-469
Category: Přehledný referát
doi: https://doi.org/10.48095/cccsnn2022462

Summary

A new era of innovative treatment options for Alzheimer‘s disease is emerging. New goals of treatment are being developed with various monoclonal antibodies targeting potentially pathological molecules involved in the pathogenesis of Alzheimer‘s disease. The aim of this review is to acquaint the reader with new potential drugs, while most of those mentioned in this review are in the third phase of clinical trials.

Keywords:

neuropsychiatric symptoms – tau protein – Alzheimer’s disease – neuroprotection – phase three testing of new drugs – β-amyloid – neuroinflammatory theory

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