Extracranially Metastasizing Meningiomas

Czech version

Authors: T. Krejčí ¹; S. Potičný ¹; T. Hrbáč ¹; R. Lipina ^1,2; Z. Večeřa ¹; J. Dvořáčková ^2,3; T. Paleček ¹
Authors‘ workplace: Neurochirurgická klinika FN Ostrava ¹; Lékařská fakulta OU v Ostravě ²; Ústav patologie FN Ostrava ³
Published in: Cesk Slov Neurol N 2013; 76/109(3): 322-328
Category: Original Paper

Overview

Aim:
The aim of the paper was to retrospectively review patients who underwent surgery for meningioma at the Neurosurgery Clinic of the University Hospital in Ostrava between 2003 and 2005, focusing on evidence of extracranial spread of meningiomas.

Material and methods:
In total, 220 patients with 227 meningiomas underwent surgery. In 196 cases (86.3%), meningiomas were grade I, grade II in 26 cases (11.5%) and grade III in 5 cases (2.2%). Convexity meningiomas dominated with 53 cases (23.3%), followed by falcine and parasagittal in 44 cases (19.4%) and other types. The disease recurred in 29 cases with the shortest follow-up of three years (3–8 years).

Results:
An extracranial metastasis was found in two patients (0.88%). A female patient with parasagittal meningioma developed solitary right lung metastasis nine years after the first surgery. A male patient with intraventricular meningioma developed solitary metastasis of the right lung with mediastinal nodal involvement within 28 months from the first surgery. Later, metastases were found in the liver. In the female patient, metastases were found during section. The male patient died 16 months after the extracranial spread of meningioma was identified. Both patients suffered from atypical meningioma that later upgraded to anaplastic meningioma.

Conclusion:
Meningiomas are rarely able to spread extracranially. However, this possibility must not be overlooked, especially in meningeomas WHO grade II and III, where such spread is relatively frequent. In our opinion, these patients should as part of routine follow-up undergo screening of the most commonly affected organs (lungs, lymph nodes, bones, abdominal organs).

Key words:
metastasis – meningioma – brain tumours

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