Surgical treatment of hormonally active hypophysial adenomas

Czech version

Authors: V. Masopust ¹; D. Netuka ¹; V. Hána ²; J. Marek ²; V. Beneš ¹
Authors‘ workplace: Neurochirurgická klinika 1. LF UK, IPVZ a ÚVN Střešovice, Praha ¹; 3. interní klinika 1. LF UK a VFN, Praha ²
Published in: Cesk Slov Neurol N 2007; 70/103(4): 402-406
Category: Short Communication

Podpořeno grantem IGA MZ ČR NR 8052-3

Overview

There had been treated 277 patients with pituitary adenoma in period from 1999 to 2003 at Department of Neurosurgery, Central Military Hospital, Prague. Altogether there had been treated 108 patients with hormone-secreting adenomas. Normalization or sufficient hormone level decrease was observed in 61 patients after the first surgery. Hormone level decrease was not sufficient in remaining cases. Second surgery was performed in 18 cases, medicamental treatment was indicated in 17 cases, radiosurgery was applied in 34 cases. There was no mortality after transsphenoidal surgery, morbidity was observed in 2 cases (visual impairment in 1 case, CSF leak in 1 case). Permanent adiuretine substitution is needed in 7 cases.

Key words:
pituitary adenoma – hormone-secreting – trassphenoidal surgery

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