Multifokální metafyzární osteonekróza kolene v důsledku pulzní léčby steroidy po ukončení léčby fingolimodem u pacientky v 19. týdnu těhotenství

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Autoři: Ayfer Ertekin
Působiště autorů: Department of Neurology, Private Siirt, Hayat Hospital, Siirt, Turkey
Vyšlo v časopise: Cesk Slov Neurol N 2021; 84/117(3): 280-281
Kategorie: Dopisy redakci
doi: https://doi.org/10.48095/cccsnn2021280

Souhrn

In MS, discontinuation of some therapies may result in increased disease activity. Fingolimod is one such agent, and severe attacks that may advance the expanded disability status scale (EDSS) may occur after the cessation of Fingolimod. Such effects may not respond to classical pulse steroid treatment [1]. High-dose pulse steroid treatments may cause osteonecrosis.

We hereby present a case of multifocal, metaphyseal osteonecrosis of the knee due to pulse steroid treatment after cessation of fingolimod treatment, which had developed in a patient who was 19 weeks pregnant.

Klíčová slova:

Pregnancy – fingolimod – osteonecrosis – pulse steroid.

Zdroje

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